PT-141
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone (α-MSH) and related to melanotan II. It is studied in research on melanocortin-receptor signaling in the central nervous system.
Key research areas
- Melanocortin (MC3R / MC4R) signaling
- Central nervous system pathways
- Hypothalamic neurobiology
- Neurotransmitter modulation
Mechanism overview
PT-141 is characterized as a selective melanocortin-receptor agonist, activating melanocortin-3 and melanocortin-4 receptors (MC3R/MC4R) in the hypothalamus and limbic regions. Downstream, research describes activation of adenylyl cyclase and cyclic AMP (cAMP) signaling, with associated modulation of dopamine, oxytocin, and norepinephrine systems.
Format and storage
Certificates of analysis
Certificates of analysis are listed per lot. None published yet.
Research use only
PT-141 is supplied for laboratory research purposes only. It is not a drug, food, dietary supplement, or cosmetic, and must not be labeled, marketed, or used as any of these. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
Purchasers are responsible for determining that their intended use complies with all applicable laws and regulations, and for ensuring that products are handled by qualified personnel under appropriate laboratory conditions.
Related products
Research use only
Apex Research supplies peptides and proteins for laboratory research. Products are not for human or veterinary use, and are not intended to diagnose, treat, cure, or prevent any disease.
By continuing, you confirm that:
- You are at least 21 years of age
- You are acquiring these products for laboratory research purposes only
- You will not administer these products to humans or animals
- You are responsible for compliance with all applicable laws and regulations in your jurisdiction